Prophylactic efficacy of combinations in hamsters against <i>L. donovani</i> challenge.

<p><i>Leishmania</i> parasite burden (number. of amastigotes per 1000 cell nuclei) in the dab smears of spleen <b>(A)</b>, liver <b>(B)</b> and bone marrow <b>(C)</b> of hamsters on days 45, 60, 90, and 120 post challenge (p.c.) Since the non-vaccinated challenged (infected control) and the <i>Bacillus Calmette Guerin</i> (BCG) alone/rLdHSP70 alone vaccinated and challenged group died after day 90 (D90) of the study period, their corresponding bars are not depicted in A, B and C. Significance values indicate the difference between the vaccinated and infected group (*, p<0.05; **, p<0.01; and ***, p<0.001).