<p><b>(A)</b> IL-12, <b>(B)</b> IFN-γ, <b>(C)</b> IL-10, and <b>(D)</b> IL-4, in PBMCs from individuals of cured VL patients (n = 8) and endemic controls (n = 8) in response to recombinant proteins individually as well as their combinations with rLdHSP70 and SLD antigens, each data point represents one individual. The results were expressed as picograms (pg) of cytokine/ml, based on the standard curves of the respective cytokine provided in the kit. The lower detection limits for various cytokines were as follows: for 5.1 pg/ml for IFN- γ, 30.8 pg/ml for IL-12, 5.1 pg/ml for IL-4 and 6.9 pg/ml for IL-10. Values are given as concentration in pg/ml.</p
<p>Dot plots showing individual cytokine responses in subjects from active VL (n = 8), cured VL (n =...
<p>DC were cultured alone (DC) or with live (zVAD treated) or apoptotic (γ-irradiated) B16 cells for...
<p>Lymphoproliferative response of PBMCs from Cured VL patients (▪), Endemic controls (▴) and health...
<p>, in response to rLdH2B, rLdH3, rLdH2A, rLdH4 and their combination and mix and SLD antigens, eac...
<p>The results are presented in the graph as for individual human sample along with horizontal bar r...
<p>(A) Real-Time PCR was used to assess IL-12p35, IL-12p40 and IL-10 mRNA on single cell levels befo...
<p>(a–d) The amount of IFNγ, IL-4, IL-10, and IL-17 secreted into the supernatant was measured by EL...
<p>Box plots (Tukey) for cytokine production by peripheral whole blood cells in response to SLA (an ...
<p>WB cultures were incubated in the presence of 100 ng/ml LPS for 20 h. In panel <b>D</b>, IL-12 (2...
<p>Cytokine concentrations were measured in cell culture supernatants using multiplex analysis. Medi...
<p>Group A was further divided into subgroups A-RV (recently vaccinated, n = 13) and A-EV (earlier v...
<p>Cytokines were measured by Luminex assay in sera of VL patients before (n = 25) and after treatme...
<p>LTT response, proliferation was represented as mean O.D of stimulated culture - mean O.D of unsti...
<p>PBMCs were purified from peripheral blood collected from asymptomatic and cured VL patients or ma...
<p>IFNγ production in SLA stimulated WB cultures of active VL patients following depletion of a) CD4...
<p>Dot plots showing individual cytokine responses in subjects from active VL (n = 8), cured VL (n =...
<p>DC were cultured alone (DC) or with live (zVAD treated) or apoptotic (γ-irradiated) B16 cells for...
<p>Lymphoproliferative response of PBMCs from Cured VL patients (▪), Endemic controls (▴) and health...
<p>, in response to rLdH2B, rLdH3, rLdH2A, rLdH4 and their combination and mix and SLD antigens, eac...
<p>The results are presented in the graph as for individual human sample along with horizontal bar r...
<p>(A) Real-Time PCR was used to assess IL-12p35, IL-12p40 and IL-10 mRNA on single cell levels befo...
<p>(a–d) The amount of IFNγ, IL-4, IL-10, and IL-17 secreted into the supernatant was measured by EL...
<p>Box plots (Tukey) for cytokine production by peripheral whole blood cells in response to SLA (an ...
<p>WB cultures were incubated in the presence of 100 ng/ml LPS for 20 h. In panel <b>D</b>, IL-12 (2...
<p>Cytokine concentrations were measured in cell culture supernatants using multiplex analysis. Medi...
<p>Group A was further divided into subgroups A-RV (recently vaccinated, n = 13) and A-EV (earlier v...
<p>Cytokines were measured by Luminex assay in sera of VL patients before (n = 25) and after treatme...
<p>LTT response, proliferation was represented as mean O.D of stimulated culture - mean O.D of unsti...
<p>PBMCs were purified from peripheral blood collected from asymptomatic and cured VL patients or ma...
<p>IFNγ production in SLA stimulated WB cultures of active VL patients following depletion of a) CD4...
<p>Dot plots showing individual cytokine responses in subjects from active VL (n = 8), cured VL (n =...
<p>DC were cultured alone (DC) or with live (zVAD treated) or apoptotic (γ-irradiated) B16 cells for...
<p>Lymphoproliferative response of PBMCs from Cured VL patients (▪), Endemic controls (▴) and health...