Effects of androgen on cell cycle-regulatory proteins in LNCaP 104-R1, PC-3<sup>LNCX-2</sup>, PC-3<sup>AR</sup>, and PC-3<sup>LNCaP-AR</sup> cells.
- John M. Kokontis (421497)
- Hui-Ping Lin (184894)
- Shih Sheng Jiang (184899)
- Ching-Yu Lin (151493)
- Junichi Fukuchi (637535)
- Richard A. Hiipakka (421491)
- Chi-Jung Chung (308827)
- Tzu-Min Chan (562577)
- Shutsung Liao (637536)
- Chung-Ho Chang (584582)
- Chih-Pin Chuu (3944804)
Publication date
October 2014
DOIAbstract
<p>Protein expression of AR, Skp2, Cdk2, phospho-Cdk2 Tyr15, phospho-Cdk2 Thr14, phospho-Cdk2 Thr160, Cdk7, cyclin E, cyclinA, cyclin H, p21<sup>cip</sup>, p27<sup>Kip</sup>, c-Myc, and E2F-1 was determined by Western blotting assay in LNCaP 104-R1, PC-3<sup>LNCX-2</sup>, PC-3<sup>AR</sup>, and PC-3<sup>LNCaP-AR</sup> cells treated with different concentration of R1881 for 96 h. Protein abundance of α-tubulin was used as loading control.</p
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