PC-KLH induced systemic production of PC-specific IgM expressing plasma cells in BLT mice.

<p>ELISPOT analyses revealed the presence of PC-specific IgM producing plasma cells in the BM (n = 6), spleen (n = 6), LN (n = 6), liver (n = 6) and lungs (n = 3) of immunized BLT mice. PC-specific IgG, KLH-specific IgM and KLH-specific IgG producing plasma cells were rare in each of the tissues sampled. Statistical analyses were 1 way ANOVA with Bonferroni's multiple comparisons tests. *** indicates a p value less than 0.001.