<div><p>Rationale</p><p>Obliterative bronchiolitis (OB) is a significant cause of morbidity and mortality after lung transplant and hematopoietic cell transplant. Mesenchymal stromal cells (MSCs) have been shown to possess immunomodulatory properties in chronic inflammatory disease.</p><p>Objective</p><p>Administration of MSCs was evaluated for the ability to ameliorate OB in mice using our established allogeneic bone marrow transplant (BMT) model.</p><p>Methods</p><p>Mice were lethally conditioned and received allogeneic bone marrow without (BM) or with spleen cells (BMS), as a source of OB-causing T-cells. Cell therapy was started at 2 weeks post-transplant, or delayed to 4 weeks when mice developed airway injury, defined as increased air...
Insult-dependent effect of bone marrow cell therapy on inflammatory response in a murine model of ex...
Abstract Introduction Administration of bone marrow-d...
The need for new options for chronic lung diseases promotes the research on stem cells for lung repa...
Obliterative bronchiolitis (OB) is a significant cause of morbidity and mortality after lung transpl...
Rationale: Obliterative bronchiolitis (OB) is a significant cause of morbidity and mortality after l...
which permits unrestricted use, distribution, and reproduction in any medium, provided the original ...
Bone marrow-derived mesenchymal stem cells (BMSCs) can ameliorate a variety of lung diseases such as...
ObjectiveBone marrow–derived mesenchymal stem cells (MSCs) have shown therapeutic potential in acute...
Bone marrow-derived mesenchymal stem cells (BMSCs) can ameliorate a variety of lung diseases such as...
Mesenchymal stromal cells (MSC) are multipotent cells with regenerative and immune-modulatory proper...
Chronic lung transplant rejection (termed chronic lung allograft dysfunction [CLAD]) is the main imp...
Obliterative bronchiolitis (OB) remains the most significant cause of death in long-term survival of...
Background: Mesenchymal stem cell (MSC) effects can shift immune responses toward anti-inflammatory ...
Background/Aims: Idiopathic pneumonia syndrome (IPS) is a serious and life-threatening lung complica...
We hypothesized that bone marrow-derived mononuclear cells (BMDMC) would attenuate the remodeling pr...
Insult-dependent effect of bone marrow cell therapy on inflammatory response in a murine model of ex...
Abstract Introduction Administration of bone marrow-d...
The need for new options for chronic lung diseases promotes the research on stem cells for lung repa...
Obliterative bronchiolitis (OB) is a significant cause of morbidity and mortality after lung transpl...
Rationale: Obliterative bronchiolitis (OB) is a significant cause of morbidity and mortality after l...
which permits unrestricted use, distribution, and reproduction in any medium, provided the original ...
Bone marrow-derived mesenchymal stem cells (BMSCs) can ameliorate a variety of lung diseases such as...
ObjectiveBone marrow–derived mesenchymal stem cells (MSCs) have shown therapeutic potential in acute...
Bone marrow-derived mesenchymal stem cells (BMSCs) can ameliorate a variety of lung diseases such as...
Mesenchymal stromal cells (MSC) are multipotent cells with regenerative and immune-modulatory proper...
Chronic lung transplant rejection (termed chronic lung allograft dysfunction [CLAD]) is the main imp...
Obliterative bronchiolitis (OB) remains the most significant cause of death in long-term survival of...
Background: Mesenchymal stem cell (MSC) effects can shift immune responses toward anti-inflammatory ...
Background/Aims: Idiopathic pneumonia syndrome (IPS) is a serious and life-threatening lung complica...
We hypothesized that bone marrow-derived mononuclear cells (BMDMC) would attenuate the remodeling pr...
Insult-dependent effect of bone marrow cell therapy on inflammatory response in a murine model of ex...
Abstract Introduction Administration of bone marrow-d...
The need for new options for chronic lung diseases promotes the research on stem cells for lung repa...