<p>Western blot, Griess reaction and ELISA assays were performed to determined iNOS and COX2 protein levels, NO production and PGE2 release in microglial N9 cells (A, C, E) and astroglial C8-D1A cells (B, D, F). Naive controls (no treatment) and LPS controls (1 µg/mL) were set up at each point. Values are mean ± SEM for three independent experiments. <sup>*</sup>p<0.05, <sup>**</sup>p<0.01 compared with corresponding sham groups.</p
COX-1 plays a previously unrecognized part in the neuroinflammation. Genetic ablation or pharmacolog...
BACKGROUND: Cyclooxygenase-2 (COX-2) is induced under inflammatory conditions, and prostaglandin E2 ...
<p>The BV2 cells were transfected with either MSS1-specfic or control siRNA for 24 h, then cells wer...
<p>Primary microglia were pretreated with or without PQQ for 1 h followed by LPS (100 ng/ml) treatme...
<p>The supernatants were collected and used for an ELISA test after sham and RF exposure. Naive cont...
<p>BV2 cells were treated with PYC at various concentrations or DMSO (vehicle) (10, 25, 50 μg/mL) fo...
<p>mRNA levels of IL-1β, TNF-α, IL-6 and CCL2 were determined by real-time PCR in microglia (A, C, E...
<p>A) iNOS expression after LPS challenge: Western-blot analysis of iNOS expression in cerebellar cu...
<p>(<b>A</b>) BV-2 cells were treated for 48 h with myr<sup>+</sup>Nef<sub>SF2</sub> (200 ng/ml) in ...
Data are presented as mean ± SEM (= 4-6). ***< 0.001 compared to the corresponding vehicle-injected ...
In this study, a panel of inhibitors with a range of selectivities for the two cyclooxygenase isofor...
Cyclooxygenases (cox) are potent mediators of inflamation and two cox-izoenzymes, cox-1, cox-2, are ...
[[abstract]]Astrocytes, the most abundant glia in the central nervous system (CNS), produce a large ...
<p>An important increase in iNOS expression in the organotypic cultures was observed in MPTP group (...
<p>Cells were pre-treated with the indicated concentrations of GLA for 1 h before incubating with LP...
COX-1 plays a previously unrecognized part in the neuroinflammation. Genetic ablation or pharmacolog...
BACKGROUND: Cyclooxygenase-2 (COX-2) is induced under inflammatory conditions, and prostaglandin E2 ...
<p>The BV2 cells were transfected with either MSS1-specfic or control siRNA for 24 h, then cells wer...
<p>Primary microglia were pretreated with or without PQQ for 1 h followed by LPS (100 ng/ml) treatme...
<p>The supernatants were collected and used for an ELISA test after sham and RF exposure. Naive cont...
<p>BV2 cells were treated with PYC at various concentrations or DMSO (vehicle) (10, 25, 50 μg/mL) fo...
<p>mRNA levels of IL-1β, TNF-α, IL-6 and CCL2 were determined by real-time PCR in microglia (A, C, E...
<p>A) iNOS expression after LPS challenge: Western-blot analysis of iNOS expression in cerebellar cu...
<p>(<b>A</b>) BV-2 cells were treated for 48 h with myr<sup>+</sup>Nef<sub>SF2</sub> (200 ng/ml) in ...
Data are presented as mean ± SEM (= 4-6). ***< 0.001 compared to the corresponding vehicle-injected ...
In this study, a panel of inhibitors with a range of selectivities for the two cyclooxygenase isofor...
Cyclooxygenases (cox) are potent mediators of inflamation and two cox-izoenzymes, cox-1, cox-2, are ...
[[abstract]]Astrocytes, the most abundant glia in the central nervous system (CNS), produce a large ...
<p>An important increase in iNOS expression in the organotypic cultures was observed in MPTP group (...
<p>Cells were pre-treated with the indicated concentrations of GLA for 1 h before incubating with LP...
COX-1 plays a previously unrecognized part in the neuroinflammation. Genetic ablation or pharmacolog...
BACKGROUND: Cyclooxygenase-2 (COX-2) is induced under inflammatory conditions, and prostaglandin E2 ...
<p>The BV2 cells were transfected with either MSS1-specfic or control siRNA for 24 h, then cells wer...