The <i>pga7^−/−</i> strain is less virulent in a mouse model of systemic candidiasis.

<p>Survival of intravenously challenged mice with <i>Candida albicans</i> strains is indicated. Groups of 5 mice were inoculated with 2 independent clones of <i>pga7^−/−</i> (KC646) or re-integrant (KC647) and were grouped together and compared to the wild type (KC645). Mice infected with the <i>pga7^−/−</i> strains survived significantly longer that mice infected with the wild type strain (p = 0.0024), whereas mice infected with the <i>PGA7</i> re-integrant strains did not survive significantly longer (p = 0.2310).