Correlation of RNAseq mRNA expression and overall survival of HNSCC patients in the TCGA dataset.

<p>Classification of stage II-III-IVa TCGA HNSCC patients according to the ABCB1 expression level in high or low. Survival analysis by Kaplan-Meier curves and log rank test of all stages together (upper left; high, n = 159; low, n = 158) or either stage II (upper right; high, n = 34; low, n = 36), stage III (lower left; high, n = 40; low, n = 41) and stage IVa (lower right; high, n = 83; low, n = 83) revealed consistently shorter survival times for patients with high ABCB1 expression, which reached significance in the whole group and the subgroup of stage IVa tumors.