PCNA labeling in histopathological liver sections.

<p>(A) Normal controls stained without primary antibody show normal liver architecture and no PCNA labeling. (B) TAA controls have many PCNA-positive hepatocyte nuclei. (C) TAA+silymarin rats have no PCNA-positive hepatocytes. (D) TAA+250 mg/kg ELAP rats have moderate hepatocyte regeneration, as indicated by moderate presence of PCNA-positive hepatocyte nuclei. (E) TAA+500 mg/kg ELAP rats have mild PCNA expression with few regenerative hepatocytes.