The average values of IC50 in MCF-7, MDA-MB231 and MCF-10A after being treated with FKA and tamoxifen, as well as the selectivity index.

AKT depletion enhances tamoxifen cytotoxicity comparable to HDAC inhibition.

Scott Thomas (431824)
K. Ted Thurn (431825)
Paromita Raha (431826)
Stephanie Chen (431827)
Pamela N. Munster (431828)

July 2013

MCF7 cells were transfected with 1 µM scramble, AKT1, AKT2, or AKT1 and 2 directed siRNA for (...

Average MxA as a potential marker of disability progression.

Federico Serana (173338)
Luisa Imberti (173344)
Maria Pia Amato (253050)
Giancarlo Comi (223051)
Claudio Gasperini (349160)
Angelo Ghezzi (551728)
Vittorio Martinelli (349163)
Leandro Provinciali (551729)
Maria Rosa Rottoli (551730)
Stefano Sotgiu (125824)
Sergio Stecchi (551731)
Michele Vecchio (551732)
Mauro Zaffaroni (551733)
Cinzia Cordioli (551734)
Ruggero Capra (173333)

April 2014

Comparison of the log2MxA values (A) and of the area under the curve for non-transform...

Effects of DOX on IC50 values of DOX in each group.

Xiaofang Zhang (181594)
Xiaojuan Wu (300616)
Peng Su (300618)
Yongsheng Gao (300620)
Bin Meng (53317)
Yanlin Sun (300622)
Li Li (14993)
Zhiqiang Zhou (300624)
Gengyin Zhou (300625)

February 2013

Cytotoxicity assays were performed as described in the “Materials and Methods”. The IC50</su...

The values of IC25, IC50 and IC75of FKA in MCF-7 and MDA-MB231 to be used in other assays.

Nadiah Abu (640291)
M. Nadeem Akhtar (640292)
Swee Keong Yeap (298365)
Kian Lam Lim (640293)
Wan Yong Ho (308639)
Aimi Jamil Zulfadli (640294)
Abdul Rahman Omar (461449)
Mohd Roslan Sulaiman (640295)
Mohd Puad Abdullah (640296)
Noorjahan Banu Alitheen (298363)

October 2014

The values of IC25, IC50 and IC75of FKA in MCF-7 and MDA-MB231 t...

The average half-maximal inhibitory concentrations (IC50) of Artonin E, and standard agents, Tamoxifen and Paclitaxel on MDA-MB 231 and MCF-10A cell lines.

Imaobong Christopher Etti (3684841)
Rasedee Abdullah (750445)
Arifah Kadir (4329949)
Najihah Mohd Hashim (656201)
Swee Keong Yeap (298365)
Mustapha Umar Imam (4329940)
Faiqah Ramli (747582)
Ibrahim Malami (3684838)
Kian Lim Lam (4329952)
Ubong Etti (4329943)
Peter Waziri (3684832)
Marsitoh Rahman (4329946)

August 2017

The average half-maximal inhibitory concentrations (IC50) of Artonin E, and standard a...

TR-MCF7 cells and MCF7 cells susceptible to YM-1 toxicity at 48 hours but not at 4 hours; tamoxifen does not alter cytotoxicity.

John Koren III (324841)
Yoshinari Miyata (324842)
Janine Kiray (324843)
John C. O'Leary III (324844)
Lana Nguyen (324845)
Jianping Guo (299686)
Laura J. Blair (324846)
Xiokai Li (324847)
Umesh K. Jinwal (324848)
Jin Q. Cheng (251543)
Jason E. Gestwicki (324849)
Chad A. Dickey (324850)

February 2013

TR-MCF7 and parental MCF7 cells were treated for 48 hours in with 10 µM YM-1. After 48 hours, med...

Scatter plot of endoxifen sensitivity in YRI LCLs.

Liming Weng (414565)
Dana Ziliak (546974)
Bonnie LaCroix (521379)
Paul Geeleher (546975)
R. Stephanie Huang (112880)

April 2014

X axis represents the 4 treatment concentrations of endoxifen (3, 5, 7 and 10 μM) and Y axis repr...

The relationship between Ki-67 response and the prediction score.

Hiroshi Onishi (1451542)
Chihiro Udagawa (3226941)
Michiaki Kubo (128298)
Seigo Nakamura (4567186)
Sadako Akashi-Tanaka (5702825)
Takashi Kuwayama (4341469)
Chie Watanabe (5702828)
Tomoko Takamaru (5702831)
Hiroyuki Takei (1839607)
Takashi Ishikawa (206896)
Kana Miyahara (3564929)
Hiroshi Matsumoto (3020496)
Yoshie Hasegawa (394398)
Yukihide Momozawa (356235)
Siew-Kee Low (244881)
Goro Kutomi (5702834)
Hiroaki Shima (5702837)
Fukino Satomi (5702840)
Minoru Okazaki (93297)
Hisamitsu Zaha (5702843)
Mai Onomura (5702846)
Ayami Matsukata (5702849)
Yasuaki Sagara (5702852)
Shinichi Baba (5702855)
Akimitsu Yamada (5702858)
Kazuhiro Shimada (5702861)
Daisuke Shimizu (1942963)
Koichiro Tsugawa (697601)
Arata Shimo (5702864)
Mikael Hartman (77255)
Ching-Wan Chan (5702867)
Soo Chin Lee (593523)
Itaru Endo (577527)
Hitoshi Zembutsu (244885)

August 2018

Prediction score was significantly associated with the Ki-67 response in breast cancer tissues after...

Tumor volume and ADC changes following tamoxifen therapy.

Guihua Zhai (583105)
Clinton J. Grubbs (583106)
Cecil R. Stockard (583107)
Heidi R. Umphrey (583108)
T. Mark Beasley (274740)
Hyunki Kim (462578)

May 2013

(A) Volume changes of tumors sensitive, intermediate, or resistant to tamoxifen over 32 days afte...

Induction of apoptosis in MCTS cultures of MCF-7 after 4-day exposure to different concentrations of tamoxifen.

Wan Yong Ho (308639)
Swee Keong Yeap (298365)
Chai Ling Ho (308641)
Raha Abdul Rahim (308644)
Noorjahan Banu Alitheen (298363)

February 2013

*Statistical significance (P<0.05) between control cells and treatment groups.</p

Overall selectivity comparisons for geldanamycin and its derivatives with varying pKa.

Rosemary A. Ndolo (123942)
Yepeng Luan (123947)
Shaofeng Duan (123953)
M. Laird Forrest (123959)
Jeffrey P. Krise (123965)

November 2012

Overall selectivity represents the IC50 for a derivative in normal human fibroblasts d...

The effect of STAT inhibitors (EGCG, Stattic, or WP1066) combined with tamoxifen on MCF-7, MCF-7/LCC1 (LCC1), and MCF-7/LCC9 (LCC9) cells in the presence of estrogen.

Rui Huang (141490)
Dana Faratian (171110)
Andrew H. Sims (108040)
Danielle Wilson (550968)
Jeremy S. Thomas (550969)
David J. Harrison (171106)
Simon P. Langdon (207293)

April 2014

Cells were grown in charcoal-stripped serum, 48 h prior to treatment and were treated with contro...

An Antiestrogenic Activity Score for tamoxifen and its metabolites is associated with breast cancer outcome

de Vries Schultink, Aurelia H M
Alexi, X
van Werkhoven, E.
Madlensky, L
Natarajan, L
Flatt, S W
Zwart, Wilbert
Linn, Sabine C.
Parker, B A
Wu, A H B
Pierce, J P
Huitema, Alwin D R
Beijnen, J H

February 2017

PURPOSE: Endoxifen concentrations have been associated with breast cancer recurrence in tamoxifen-tr...

The effect of STAT inhibitors (A. EGCG, B. WP1066 and C. Stattic) on proliferation of Tamoxifen sensitive and resistant (MCF-7, MCF-7/LCC1 (LCC1), and MCF-7/LCC9 (LCC9)) cells.

Rui Huang (141490)
Dana Faratian (171110)
Andrew H. Sims (108040)
Danielle Wilson (550968)
Jeremy S. Thomas (550969)
David J. Harrison (171106)
Simon P. Langdon (207293)

April 2014

All cells were incubated in double charcoal-stripped medium for another 48 h after seeding and tr...

Selective Cytotoxicity of UA to tumorigenic MCF-7 over non tumorigenic MCF 10A.

Tripti Mishra (773049)
Rakesh Kumar Arya (3147594)
Sanjeev Meena (773051)
Pushpa Joshi (3147588)
Mahesh Pal (773050)
Baleshwar Meena (773054)
D. K. Upreti (3147591)
T. S. Rana (3147597)
Dipak Datta (773052)

July 2016

Percentage growth inhibition and IC50 of UA in different breast cancer cell lines. MCF...

AKT depletion enhances tamoxifen cytotoxicity comparable to HDAC inhibition.

Scott Thomas (431824)
K. Ted Thurn (431825)
Paromita Raha (431826)
Stephanie Chen (431827)
Pamela N. Munster (431828)

July 2013

MCF7 cells were transfected with 1 µM scramble, AKT1, AKT2, or AKT1 and 2 directed siRNA for (...

Average MxA as a potential marker of disability progression.

Federico Serana (173338)
Luisa Imberti (173344)
Maria Pia Amato (253050)
Giancarlo Comi (223051)
Claudio Gasperini (349160)
Angelo Ghezzi (551728)
Vittorio Martinelli (349163)
Leandro Provinciali (551729)
Maria Rosa Rottoli (551730)
Stefano Sotgiu (125824)
Sergio Stecchi (551731)
Michele Vecchio (551732)
Mauro Zaffaroni (551733)
Cinzia Cordioli (551734)
Ruggero Capra (173333)

April 2014

Comparison of the log2MxA values (A) and of the area under the curve for non-transform...

Effects of DOX on IC50 values of DOX in each group.

Xiaofang Zhang (181594)
Xiaojuan Wu (300616)
Peng Su (300618)
Yongsheng Gao (300620)
Bin Meng (53317)
Yanlin Sun (300622)
Li Li (14993)
Zhiqiang Zhou (300624)
Gengyin Zhou (300625)

February 2013

Cytotoxicity assays were performed as described in the “Materials and Methods”. The IC50</su...

The values of IC25, IC50 and IC75of FKA in MCF-7 and MDA-MB231 to be used in other assays.

Nadiah Abu (640291)
M. Nadeem Akhtar (640292)
Swee Keong Yeap (298365)
Kian Lam Lim (640293)
Wan Yong Ho (308639)
Aimi Jamil Zulfadli (640294)
Abdul Rahman Omar (461449)
Mohd Roslan Sulaiman (640295)
Mohd Puad Abdullah (640296)
Noorjahan Banu Alitheen (298363)

October 2014

The values of IC25, IC50 and IC75of FKA in MCF-7 and MDA-MB231 t...

The average half-maximal inhibitory concentrations (IC50) of Artonin E, and standard agents, Tamoxifen and Paclitaxel on MDA-MB 231 and MCF-10A cell lines.

Imaobong Christopher Etti (3684841)
Rasedee Abdullah (750445)
Arifah Kadir (4329949)
Najihah Mohd Hashim (656201)
Swee Keong Yeap (298365)
Mustapha Umar Imam (4329940)
Faiqah Ramli (747582)
Ibrahim Malami (3684838)
Kian Lim Lam (4329952)
Ubong Etti (4329943)
Peter Waziri (3684832)
Marsitoh Rahman (4329946)

August 2017

The average half-maximal inhibitory concentrations (IC50) of Artonin E, and standard a...

TR-MCF7 cells and MCF7 cells susceptible to YM-1 toxicity at 48 hours but not at 4 hours; tamoxifen does not alter cytotoxicity.

John Koren III (324841)
Yoshinari Miyata (324842)
Janine Kiray (324843)
John C. O'Leary III (324844)
Lana Nguyen (324845)
Jianping Guo (299686)
Laura J. Blair (324846)
Xiokai Li (324847)
Umesh K. Jinwal (324848)
Jin Q. Cheng (251543)
Jason E. Gestwicki (324849)
Chad A. Dickey (324850)

February 2013

TR-MCF7 and parental MCF7 cells were treated for 48 hours in with 10 µM YM-1. After 48 hours, med...

Scatter plot of endoxifen sensitivity in YRI LCLs.

Liming Weng (414565)
Dana Ziliak (546974)
Bonnie LaCroix (521379)
Paul Geeleher (546975)
R. Stephanie Huang (112880)

April 2014

X axis represents the 4 treatment concentrations of endoxifen (3, 5, 7 and 10 μM) and Y axis repr...

The relationship between Ki-67 response and the prediction score.

Hiroshi Onishi (1451542)
Chihiro Udagawa (3226941)
Michiaki Kubo (128298)
Seigo Nakamura (4567186)
Sadako Akashi-Tanaka (5702825)
Takashi Kuwayama (4341469)
Chie Watanabe (5702828)
Tomoko Takamaru (5702831)
Hiroyuki Takei (1839607)
Takashi Ishikawa (206896)
Kana Miyahara (3564929)
Hiroshi Matsumoto (3020496)
Yoshie Hasegawa (394398)
Yukihide Momozawa (356235)
Siew-Kee Low (244881)
Goro Kutomi (5702834)
Hiroaki Shima (5702837)
Fukino Satomi (5702840)
Minoru Okazaki (93297)
Hisamitsu Zaha (5702843)
Mai Onomura (5702846)
Ayami Matsukata (5702849)
Yasuaki Sagara (5702852)
Shinichi Baba (5702855)
Akimitsu Yamada (5702858)
Kazuhiro Shimada (5702861)
Daisuke Shimizu (1942963)
Koichiro Tsugawa (697601)
Arata Shimo (5702864)
Mikael Hartman (77255)
Ching-Wan Chan (5702867)
Soo Chin Lee (593523)
Itaru Endo (577527)
Hitoshi Zembutsu (244885)

August 2018

Prediction score was significantly associated with the Ki-67 response in breast cancer tissues after...

Tumor volume and ADC changes following tamoxifen therapy.

Guihua Zhai (583105)
Clinton J. Grubbs (583106)
Cecil R. Stockard (583107)
Heidi R. Umphrey (583108)
T. Mark Beasley (274740)
Hyunki Kim (462578)

May 2013

(A) Volume changes of tumors sensitive, intermediate, or resistant to tamoxifen over 32 days afte...

Induction of apoptosis in MCTS cultures of MCF-7 after 4-day exposure to different concentrations of tamoxifen.

Wan Yong Ho (308639)
Swee Keong Yeap (298365)
Chai Ling Ho (308641)
Raha Abdul Rahim (308644)
Noorjahan Banu Alitheen (298363)

February 2013

*Statistical significance (P<0.05) between control cells and treatment groups.</p

Overall selectivity comparisons for geldanamycin and its derivatives with varying pKa.

Rosemary A. Ndolo (123942)
Yepeng Luan (123947)
Shaofeng Duan (123953)
M. Laird Forrest (123959)
Jeffrey P. Krise (123965)

November 2012

Overall selectivity represents the IC50 for a derivative in normal human fibroblasts d...

The effect of STAT inhibitors (EGCG, Stattic, or WP1066) combined with tamoxifen on MCF-7, MCF-7/LCC1 (LCC1), and MCF-7/LCC9 (LCC9) cells in the presence of estrogen.

Rui Huang (141490)
Dana Faratian (171110)
Andrew H. Sims (108040)
Danielle Wilson (550968)
Jeremy S. Thomas (550969)
David J. Harrison (171106)
Simon P. Langdon (207293)

April 2014

Cells were grown in charcoal-stripped serum, 48 h prior to treatment and were treated with contro...

An Antiestrogenic Activity Score for tamoxifen and its metabolites is associated with breast cancer outcome

de Vries Schultink, Aurelia H M
Alexi, X
van Werkhoven, E.
Madlensky, L
Natarajan, L
Flatt, S W
Zwart, Wilbert
Linn, Sabine C.
Parker, B A
Wu, A H B
Pierce, J P
Huitema, Alwin D R
Beijnen, J H

February 2017

PURPOSE: Endoxifen concentrations have been associated with breast cancer recurrence in tamoxifen-tr...

The effect of STAT inhibitors (A. EGCG, B. WP1066 and C. Stattic) on proliferation of Tamoxifen sensitive and resistant (MCF-7, MCF-7/LCC1 (LCC1), and MCF-7/LCC9 (LCC9)) cells.

Rui Huang (141490)
Dana Faratian (171110)
Andrew H. Sims (108040)
Danielle Wilson (550968)
Jeremy S. Thomas (550969)
David J. Harrison (171106)
Simon P. Langdon (207293)

April 2014

All cells were incubated in double charcoal-stripped medium for another 48 h after seeding and tr...

Selective Cytotoxicity of UA to tumorigenic MCF-7 over non tumorigenic MCF 10A.

Tripti Mishra (773049)
Rakesh Kumar Arya (3147594)
Sanjeev Meena (773051)
Pushpa Joshi (3147588)
Mahesh Pal (773050)
Baleshwar Meena (773054)
D. K. Upreti (3147591)
T. S. Rana (3147597)
Dipak Datta (773052)

July 2016

Percentage growth inhibition and IC50 of UA in different breast cancer cell lines. MCF...

AKT depletion enhances tamoxifen cytotoxicity comparable to HDAC inhibition.

Scott Thomas (431824)
K. Ted Thurn (431825)
Paromita Raha (431826)
Stephanie Chen (431827)
Pamela N. Munster (431828)

July 2013

MCF7 cells were transfected with 1 µM scramble, AKT1, AKT2, or AKT1 and 2 directed siRNA for (...

Average MxA as a potential marker of disability progression.

Federico Serana (173338)
Luisa Imberti (173344)
Maria Pia Amato (253050)
Giancarlo Comi (223051)
Claudio Gasperini (349160)
Angelo Ghezzi (551728)
Vittorio Martinelli (349163)
Leandro Provinciali (551729)
Maria Rosa Rottoli (551730)
Stefano Sotgiu (125824)
Sergio Stecchi (551731)
Michele Vecchio (551732)
Mauro Zaffaroni (551733)
Cinzia Cordioli (551734)
Ruggero Capra (173333)

April 2014

Comparison of the log2MxA values (A) and of the area under the curve for non-transform...

Effects of DOX on IC50 values of DOX in each group.

Xiaofang Zhang (181594)
Xiaojuan Wu (300616)
Peng Su (300618)
Yongsheng Gao (300620)
Bin Meng (53317)
Yanlin Sun (300622)
Li Li (14993)
Zhiqiang Zhou (300624)
Gengyin Zhou (300625)

February 2013

Cytotoxicity assays were performed as described in the “Materials and Methods”. The IC50</su...

The average values of IC<sub>50</sub> in MCF-7, MDA-MB231 and MCF-10A after being treated with FKA and tamoxifen, as well as the selectivity index.

Abstract

Extracted data

The average values of IC<sub>50</sub> in MCF-7, MDA-MB231 and MCF-10A after being treated with FKA and tamoxifen, as well as the selectivity index.

Abstract

Extracted data

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