Schematic representation of HD gene expression domains in the cuttlefish CNS.

<p>Expression territories are extrapolated from analysis of serially sectioned embryos from stages E24–28 (this paper) and previously published data^* °. Dorsal view of the head is shown on the left, and lateral view on the right as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0109627#pone-0109627-g001" target="_blank">Figure 1</a>. Territories with potentially overlapping expression domains are multi-coloured. A) ANTP-class Hox genes <i>Sof-Hox3</i> (dark green), <i>Sof-Gbx</i> (orange), and <i>Sof-Mnx*</i> (pink). B) PRD-class genes <i>Sof-Arx</i> (red), <i>Sof-Vsx</i> (dark blue), <i>Sof-Phox2*</i> (light green), and <i>Sof-otx</i>° (yellow). C) LIM-class gene <i>Sof-Lhx3/4</i> (light blue). Note that ANTP-class genes are largely restricted to the subesophageal masses, whereas PRD-class genes are more expansive within the supraesophageal mass. Both <i>Sof-Hox3</i> and <i>Sof-Lhx3/4</i> show extensive expression throughout the nervous system, and five of the eight genes represented here are found within the stellate ganglion. Abbreviations are as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0109627#pone-0109627-g001" target="_blank">Figure 1</a>; * data extrapolated from Nomaksteinsky <i>et al</i>. <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0109627#pone.0109627-Nomaksteinsky1" target="_blank">[26]</a> for stage E29 embryos; ° data extrapolated from Buresi <i>et al.</i><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0109627#pone.0109627-Buresi2" target="_blank">[25]</a> for embryos at stages E25–26.