<p><b>A–C</b>. MDMs were infected with LVS (A), Schu S4 (B), or U112 (C) 48 h after transfection with miR-155-specific or negative control pre-miRs, and viable intracellular bacteria were quantified at the indicated time points by measurement of CFU. Data shown are the mean ±SEM (n = 3). <b>D</b>. LVS replicates normally in control (xBlue) and MyD88-deficient (x-Blue-def MyD88) THP-1 macrophages. Data are the mean ±SEM (n = 3).</p
<p>Differential expression analysis of microRNAs was carried out by TLDA (Applied Biosystems) using ...
Background: Due to their role in fine-tuning cellular protein expression, microRNAs both promote vir...
<p>MiR-210 expression at 3, 6, 12, and 24 h in infected cells relatively to non-infected cells (pane...
<p><b>A</b>. MDMs were infected with <i>F. tularensis</i> LVS, <i>F. tularensis</i> Schu S4 or <i>F....
<div><p><i>Francisella tularensis</i> is a Gram-negative, facultative intracellular pathogen that re...
<p><i>F. tularensis</i> lipoproteins trigger TLR2 signaling in macrophages <a href="http://www.ploso...
<p>(A–C) RAW264.7 cells were transfected with control or miR-155 mimic for 24 h followed by BCG (A),...
<p>(A) PBM were infected with live, heat-killed (HK), or paraformaldehyde-fixed (PFA) <i>F.n.</i> at...
<p>MDMs from 12 different donors were cultured for 16 h unstimulated or with the ligands for TLR3, T...
<p>(A) miR-155 expression levels were examined in the lungs of normal uninfected or H37Rv infected B...
<p>MDMs from seven different donors were transfected for 24 h (LipoRNAiMax, Invitrogen) with 30 nM a...
<p>Expression of miRNAs was determined by Taqman Real-Time PCR and expressed as mean relative expres...
<p>(A) PBM were transfected with vector control or miR-155 overexpression construct. 22 hours post-t...
<p>MDMs were transfected with negative control and miR-155 mimic (pre-miR), or with negative control...
<p>(A–D) RAW264.7 cells were transfected with miR-155 mimic (A and C) or inhibitor (B and D) for 24 ...
<p>Differential expression analysis of microRNAs was carried out by TLDA (Applied Biosystems) using ...
Background: Due to their role in fine-tuning cellular protein expression, microRNAs both promote vir...
<p>MiR-210 expression at 3, 6, 12, and 24 h in infected cells relatively to non-infected cells (pane...
<p><b>A</b>. MDMs were infected with <i>F. tularensis</i> LVS, <i>F. tularensis</i> Schu S4 or <i>F....
<div><p><i>Francisella tularensis</i> is a Gram-negative, facultative intracellular pathogen that re...
<p><i>F. tularensis</i> lipoproteins trigger TLR2 signaling in macrophages <a href="http://www.ploso...
<p>(A–C) RAW264.7 cells were transfected with control or miR-155 mimic for 24 h followed by BCG (A),...
<p>(A) PBM were infected with live, heat-killed (HK), or paraformaldehyde-fixed (PFA) <i>F.n.</i> at...
<p>MDMs from 12 different donors were cultured for 16 h unstimulated or with the ligands for TLR3, T...
<p>(A) miR-155 expression levels were examined in the lungs of normal uninfected or H37Rv infected B...
<p>MDMs from seven different donors were transfected for 24 h (LipoRNAiMax, Invitrogen) with 30 nM a...
<p>Expression of miRNAs was determined by Taqman Real-Time PCR and expressed as mean relative expres...
<p>(A) PBM were transfected with vector control or miR-155 overexpression construct. 22 hours post-t...
<p>MDMs were transfected with negative control and miR-155 mimic (pre-miR), or with negative control...
<p>(A–D) RAW264.7 cells were transfected with miR-155 mimic (A and C) or inhibitor (B and D) for 24 ...
<p>Differential expression analysis of microRNAs was carried out by TLDA (Applied Biosystems) using ...
Background: Due to their role in fine-tuning cellular protein expression, microRNAs both promote vir...
<p>MiR-210 expression at 3, 6, 12, and 24 h in infected cells relatively to non-infected cells (pane...