Correlation of the error threshold with average number of 1–Hamming distance neighbours.

<p>Critical per digit replication accuracy of SSCs as a function of the average number of 1–Hamming distance neighbours for sequences in the SSC. Red curves show fit of Eq. 3 to the data points, while the dark gray curve show fit to Eq. 3 with no back-mutations (). Results are for (left) and (right). The average number of 1HD neighbours can be transformed to by dividing it by the length of the sequence.