MMP-12 deficiency inhibits production of PDGFBB, TGFβ1 and pSMAD2 in the Ang II treated skin and heart.

<p>A. IHC staining of PDGFBB, TGFβ1 and pSMAd2 was performed on paraffin sections from the skin. B. Immunofluorescence staining of TGFβ1 was performed on cryosections from the heart. Representative photographs are shown from four animals per group.