Photographic evolution of the human skin graft in mice.

<p><b>A, human full-thickness skin graft evolution from the control group.</b> (a) Day of surgery. (b) Day 6 after surgery. (c) Day 30 after surgery. (d) Day 60 after surgery. Macroscopically, the graft was soft and pliable, resembling normal human skin. Note that the stable human full-thickness skin graft from the control groups took successfully. B, human full-thickness skin graft evolution after placing the compression device for three cycles. (a) Day before the compression device was applied. (b) Day 1 after the three compression cycles. The human skin graft remained folded with a hemorrhagic area in the center of the fold (see arrow). (c) Day 7 after compression cycles. Irreversible damage characterizing a PU can be observed. The center of the fold was occupied by a necrotic and hemorrhagic area (see arrow). (d) Day 31 after the compression cycles. Crusty remnants were observed. (e) Day 40 after compression cycles. Only a small central crusted island could be observed. (f) Day 130 after compression cycles. Complete regeneration of the graft was noticed.