Comparison of predictive ability of tissue-specific insulin resistance indices with fasting plasma insulin levels at baseline in predicting worsening of hyperglycemia at the 5.9-years METSIM follow-up study, Kuopio, Finland.

<p>Abbreviations: Beta, standardized regression coefficient; FPG, fasting plasma glucose; Glucose AUC, glucose area under the curve; 2hPG, 2-hour plasma glucose; IR, insulin resistance.</p><p>Beta was obtained from linear regression analysis. The difference between the standardized coefficients of IR indices and fasting insulin was tested using Fisheŕs r-to-z transformation. Individuals with type 1 diabetes (N = 25), with known type 2 diabetes (N = 763), newly diagnosed type 2 diabetes at baseline (N = 649) or diagnosed with diabetes between baseline and follow-up (N = 117) were excluded, N = 4,474 for FPG and 2hPG, and 4,450 for glucose AUC. Bold font indicates statistical significance <i>P</i><0.0125. <i>P</i>, unadjusted.</p><p>*Matsuda IR was calculated as: 10/Matsuda ISI.</p><p>Comparison of predictive ability of tissue-specific insulin resistance indices with fasting plasma insulin levels at baseline in predicting worsening of hyperglycemia at the 5.9-years METSIM follow-up study, Kuopio, Finland.