The effect of TRPC3 KO on vasoconstriction of ECs intact mesenteric arteries.

<p>A1. Representative recordings of the differences in phenylephrine-induced vasoconstriction between WT and TRPC3 KO mice. A2. Mean data for phenylephrine-induced vasoconstriction in WT and TRPC3 KO mice (n = 8–9). B. Mean data for 70 mmol/L KCl-induced vasoconstriction in WT and TRPC3 KO mice (n = 12–14). Vessel diameter was measured at an intraluminal pressure of 40 mmHg, C1. Representative recordings of the differencesin pressure-induced myogenic tone between WT and TRPC3 KO mice. C2. Mean data for pressure-induced myogenic tone in WT and TRPC3 KO mice (n = 6–8). Data are expressed as mean ± SEM. *<i>P</i><0.05. ILP: intraluminal pressure.