Restoration of ATP, NADPH and γ-glutamylcysteinyl ligase catalytic subunit activity in hippocampus following Withanolide A during hypoxia.

<p>Hypoxic exposure for 7 days decreases the hippocampal ATP, NADPH and γ-glutamylcysteinyl ligase catalytic subunit activity while administration of Withanolide A increases the ATP, NADPH and γ-glutamylcysteinyl ligase catalytic subunit activity in hippocampus. Data expressed as percentage change taking normoxic value as 100% and represents Mean ± SEM. ‘a’ denotes p≤0.05 vs. when compared to normoxic group and ‘b’ denotes p≤0.05 vs. when compared to 7 days hypoxic group treated with vehicle only.