<p>Withanolide A administration during hypoxic exposure increases hypoxia induced decreased activity of glutathione reductase, glutathione peroxidase, glutathione s transferase and superoxide dismutase in hippocampus. Data expressed as percentage change taking normoxic value as 100% and represents Mean ± SEM. ‘a’ denotes p≤0.05 vs. when compared to normoxic group and ‘b’ denotes p≤0.05 vs. when compared to 7 days hypoxic group treated with vehicle only.</p
<p>a = p≤0.05 vs control group; b = p≤0.05 vs DMBA group; c = p≤0.05 vs I3C group; d = p≤0.0...
<p><b>Effect of XO inhibition by allopurinol (50mg/kg) on activity of antioxidant enzymes in erythro...
The effect of aglycaemic hypoxia (AH) on the activity of the mitochondrial respiratory chain complex...
<p>Administration of Withanolide A decreases the hypoxia induced elevated level of reactive oxygen s...
<p>Withanolide A effectively decreases the number of degenerating neurons caused by hypoxic exposure...
<p>Administration of withanolide A prior to and during hypoxic exposure decreases number of apoptoti...
<p>Hypoxic exposure for 7 days decreases the hippocampal ATP, NADPH and γ-glutamylcysteinyl ligase c...
<p>Withanolide A administration during hypoxic exposure upregulates Nrf2 and GCLC expression in hipp...
Withania somnifera root extract has been used traditionally in ayurvedic system of medicine as a mem...
<div><p><i>Withania somnifera</i> root extract has been used traditionally in ayurvedic system of me...
<p>Exposure to hypobaric hypoxia increased (i) path length and (ii) latency during spatial memory te...
<p>Schematic diagram showing Withanolide A mediated modulation of glutathione biosynthesis and neuro...
Oxidative stress is associated with the pathology of acute and chronic neurodegenerative disease. Cu...
The effect of Ca2+-homopantothenate (HOPA) treatment (250 mg/kg for 5 d) has been studied by evaluat...
The adaptation to repeated, alternate normobaric hypoxic and normoxic exposures (12 h/day, for 5 day...
<p>a = p≤0.05 vs control group; b = p≤0.05 vs DMBA group; c = p≤0.05 vs I3C group; d = p≤0.0...
<p><b>Effect of XO inhibition by allopurinol (50mg/kg) on activity of antioxidant enzymes in erythro...
The effect of aglycaemic hypoxia (AH) on the activity of the mitochondrial respiratory chain complex...
<p>Administration of Withanolide A decreases the hypoxia induced elevated level of reactive oxygen s...
<p>Withanolide A effectively decreases the number of degenerating neurons caused by hypoxic exposure...
<p>Administration of withanolide A prior to and during hypoxic exposure decreases number of apoptoti...
<p>Hypoxic exposure for 7 days decreases the hippocampal ATP, NADPH and γ-glutamylcysteinyl ligase c...
<p>Withanolide A administration during hypoxic exposure upregulates Nrf2 and GCLC expression in hipp...
Withania somnifera root extract has been used traditionally in ayurvedic system of medicine as a mem...
<div><p><i>Withania somnifera</i> root extract has been used traditionally in ayurvedic system of me...
<p>Exposure to hypobaric hypoxia increased (i) path length and (ii) latency during spatial memory te...
<p>Schematic diagram showing Withanolide A mediated modulation of glutathione biosynthesis and neuro...
Oxidative stress is associated with the pathology of acute and chronic neurodegenerative disease. Cu...
The effect of Ca2+-homopantothenate (HOPA) treatment (250 mg/kg for 5 d) has been studied by evaluat...
The adaptation to repeated, alternate normobaric hypoxic and normoxic exposures (12 h/day, for 5 day...
<p>a = p≤0.05 vs control group; b = p≤0.05 vs DMBA group; c = p≤0.05 vs I3C group; d = p≤0.0...
<p><b>Effect of XO inhibition by allopurinol (50mg/kg) on activity of antioxidant enzymes in erythro...
The effect of aglycaemic hypoxia (AH) on the activity of the mitochondrial respiratory chain complex...