IL-18 in critically ill patients after ICU admission.

<p>A) Urinary IL-18 levels assessed by ELISA from AKI and no-AKI patients. Every point represents the biomarker value in each urine sample, and the lines depicted the mean and 95% confident interval. AVG = average of urinary IL-18 levels in no-AKI patients determinated at 1, 5, and 10 days after ICU admission. B) Specificity and sensitivity of IL-18 to detect AKI two days before the AKIN criteria, determined by ROC analysis. C) Specificity and sensitivity of IL-18 to detect AKI one day before the AKIN criteria, determined by ROC analysis.