Electron-Rich Aromatics Under Ball Milling: Oxidative Aryl-iodination Using I₂-Oxone and Biarylation with I₂

<div><p></p><p>We report here a simple, efficient, and environmentally friendly methodology for electrophilic aryl-iodination of electron-rich arenes using I₂-oxone under ball milling. The reactions work efficiently under solvent-free conditions at room temperature. We have also shown that iodine could be used as catalyst for metal-free biaryl coupling of a few electron-rich substrates. In addition, one-pot multistep synthesis has been demonstrated for one substrate.</p>