Overexpression of miR-137 promoted bladder cancer cell proliferation, migration and invasion.

<p>(A) Expression levels of miR-137 were examined by real-time PCR after transfection of miR-137 mimics or sramble or no transfection. (B) Growth of T24 cells was shown after transfection with miR-137 mimics or sramble or no transfection. The growth index as assessed at 0, 24, 48 and 72 h. (C) Expression levels of miR-137 were examined by real-time PCR after transfection of miR-137 inhibitor or control or no transfection. (D) Growth of T24 cells was shown after transfection with miR-137 inhibitor or control or no transfection. The growth index as assessed at 0, 24, 48 and 72 h. (E) Transwell analysis of T24 cells after treatment with miR-137 mimics, inhibitors or scramble or control; the relative ratio of migrated cells per field is shown below. (D) Transwell analysis of T24 cells after treatment with miR-137 mimics, inhibitors or scramble or control; the relative ratio of invasive cells per field is shown below, *p<0.05, **p<0.01, and ***p<0.001.