Gain-of-function <i>unc-104</i> motor mutations suppress <i>sam-4</i> and <i>syd-2</i> SV trafficking defects.

<p>(A–G′) shown is the distribution of GFP-RAB-3 accumulations in PLM synaptic varicosities (left) and the PLM soma and proximal neurite (right). Arrowheads: PLM synaptic varicosities; solid arrows: PLM soma; open arrows: PLM neurites. Scale bar: 20 µm. (H–I) Quantification of GFP-RAB-3 fluorescence intensity in PLM synaptic varicosities. **, P<0.001 relative to wild type; ΔΔ, P<0.001 relative to <i>sam-4(js415)</i>; §§, P<0.001 relative to <i>syd-2(ok217)</i>.