<p>Cells were incubated for 3 h/37°C with <sup>59</sup>Fe-transferrin (0.75 µM), washed 4 times with ice-cold PBS and then reincubated for 3 h/37°C in the presence or absence of the chelators (25 µM). Release of <sup>59</sup>Fe was then assessed using a γ-scintillation counter. Results are mean ±SD (3 experiments).</p
Transferrin is a plasma iron transport protein responsible for binding iron released from the breakd...
<p>Progress curves were recorded at 460 nm for formation of diferric-transferrin and the initial rat...
<p>Chelators at iron-binding equivalent (IBE) ratios of 0.1, 1, and 3 were incubated in the presence...
<p>Cells were incubated for 3 h/37°C with <sup>59</sup>Fe-transferrin (0.75 µM) in the presence or a...
<p>(<b>A</b>) The ability of the ligands to promote <sup>59</sup>Fe mobilization from MCF-7 cells wa...
AbstractIron (Fe) chelators of the pyridoxal isonicotinoyl hydrazone (PIH) class may be useful agent...
<p>THP-1 cells incubated in the presence of MCP-1 (A) and Rantes (B). Cell migration determined by f...
<p>Cell proliferation was analyzed using the MTT assay. Cells were treated with 82, 410, or 820 µg/m...
<p>(<b>A</b>) Fe(III) uptake by live HL-1 cells treated at 3 indicated doses, detected by CALG-AM fl...
<p>(A) Effect of 2 h FeCl<sub>2</sub> pre-incubation (FeCl<sub>2</sub> p) (dotted line) or co-incuba...
<p>Intracellular iron was quantified using a colorimetric assay one hour after the addition of 50 µM...
<p>Dose response curves for iron complex (FeNG) using (A) CEM/ADR5000 (B) CCRF-CEM, and (C) Human PB...
AbstractRecent studies have demonstrated that preincubation of SK-Mel-28 melanoma cells with ferric ...
Iron in man is held within the cells incorporated in organic complex molecules, either as functional...
The experiments contained within this thesis have characterized the ability of desferrioxamine (DFO)...
Transferrin is a plasma iron transport protein responsible for binding iron released from the breakd...
<p>Progress curves were recorded at 460 nm for formation of diferric-transferrin and the initial rat...
<p>Chelators at iron-binding equivalent (IBE) ratios of 0.1, 1, and 3 were incubated in the presence...
<p>Cells were incubated for 3 h/37°C with <sup>59</sup>Fe-transferrin (0.75 µM) in the presence or a...
<p>(<b>A</b>) The ability of the ligands to promote <sup>59</sup>Fe mobilization from MCF-7 cells wa...
AbstractIron (Fe) chelators of the pyridoxal isonicotinoyl hydrazone (PIH) class may be useful agent...
<p>THP-1 cells incubated in the presence of MCP-1 (A) and Rantes (B). Cell migration determined by f...
<p>Cell proliferation was analyzed using the MTT assay. Cells were treated with 82, 410, or 820 µg/m...
<p>(<b>A</b>) Fe(III) uptake by live HL-1 cells treated at 3 indicated doses, detected by CALG-AM fl...
<p>(A) Effect of 2 h FeCl<sub>2</sub> pre-incubation (FeCl<sub>2</sub> p) (dotted line) or co-incuba...
<p>Intracellular iron was quantified using a colorimetric assay one hour after the addition of 50 µM...
<p>Dose response curves for iron complex (FeNG) using (A) CEM/ADR5000 (B) CCRF-CEM, and (C) Human PB...
AbstractRecent studies have demonstrated that preincubation of SK-Mel-28 melanoma cells with ferric ...
Iron in man is held within the cells incorporated in organic complex molecules, either as functional...
The experiments contained within this thesis have characterized the ability of desferrioxamine (DFO)...
Transferrin is a plasma iron transport protein responsible for binding iron released from the breakd...
<p>Progress curves were recorded at 460 nm for formation of diferric-transferrin and the initial rat...
<p>Chelators at iron-binding equivalent (IBE) ratios of 0.1, 1, and 3 were incubated in the presence...