Values are mean ± SEM methylation of individual CpG loci at baseline in the 5′ regulatory regions of (A) FADS2, (B) FADS1, (C) ELOVL5 and (D) ELOVL2 in PBMCs from male (open bars) and female (closed bars) subjects in the Study 1 cohort.

<p>Numbers of subjects are listed in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0109896#pone-0109896-t001" target="_blank">Table 1</a>. Locations of individual CpG dinucleotides are relative to the transcription start site (TSS). Dotted horizontal line indicates the analytical limit of the assay.