<p>PBMC or purified monocytes derived from HC were stimulated for 18 hours with the indicated cytokines or synovial fluid and expression of indicated molecules were analyzed by flow cytometry (<b>A</b>). Representative flow cytometric analysis of CD80 expression on monocytes treated with the indicated cytokines [left; solid line: IFN-γ (25 ng/ml), dashed line: IFN-γ plus TGF-β, dotted line: no cytokine, gray shaded: isotype control]. The change in CD80 expression on monocytes treated with various combinations of cytokines (right; n = 6). MFI, mean fluorescent intensity. (<b>B</b>). Quantitative RT-PCR analysis of CD80 gene expression on monocytes after treatment with IFN-γ alone or IFN-γ plus TGF-β (n = 3). (<b>C</b>) The change in HLA-DR e...
<p>Mononuclear cells were isolated from PB. Synovial tissue (ST) samples were obtained at arthroscop...
Objectives: This study, developed within the Innovative Medicines Initiative Joint Undertaking proje...
<p>A) Thawed A) Cryopreserved PBMC from control and RA patients were stimulated for 4hrs with LPS (1...
<p>(<b>A</b>) Quantitative RT-PCR analysis of CD68, CD80, CD86, and CD276 gene expression in paired ...
<p>PBMC or purified monocytes derived from HC were stimulated for 18 hours with the indicated TLR ag...
Monocytes function as crucial innate effectors in the pathogenesis of chronic inflammatory diseases,...
<p>(<b>A</b>) Representative contour plot of CD14 and CD16 expression on paired peripheral (left) an...
<p>(<b>A</b>) Quantitative RT-PCR analysis of CX<sub>3</sub>CR1, CCR2, and CCR5 gene expression in p...
Objectives: To investigate the ability of synovial fluid from patients with rheumatoid arthritis (RA...
Objectives: To investigate the ability of synovial fluid from patients with rheumatoid arthritis (RA...
Objectives: To investigate the ability of synovial fluid from patients with rheumatoid arthritis (RA...
<p>Monocytes and CD4<sup>+</sup> memory T cells were isolated from peripheral blood and synovial flu...
<p><b>A)</b> Single cell suspensions were prepared from synovial biopsies from RA patients (n = 4) a...
<p>Comparisons of the percentages and mean fluorescence intensity (MFI) of circulating MDL-1-express...
<p><b>A</b>) Representative forward and side scatter of synovial fluid cells (SFCs) with gating of l...
<p>Mononuclear cells were isolated from PB. Synovial tissue (ST) samples were obtained at arthroscop...
Objectives: This study, developed within the Innovative Medicines Initiative Joint Undertaking proje...
<p>A) Thawed A) Cryopreserved PBMC from control and RA patients were stimulated for 4hrs with LPS (1...
<p>(<b>A</b>) Quantitative RT-PCR analysis of CD68, CD80, CD86, and CD276 gene expression in paired ...
<p>PBMC or purified monocytes derived from HC were stimulated for 18 hours with the indicated TLR ag...
Monocytes function as crucial innate effectors in the pathogenesis of chronic inflammatory diseases,...
<p>(<b>A</b>) Representative contour plot of CD14 and CD16 expression on paired peripheral (left) an...
<p>(<b>A</b>) Quantitative RT-PCR analysis of CX<sub>3</sub>CR1, CCR2, and CCR5 gene expression in p...
Objectives: To investigate the ability of synovial fluid from patients with rheumatoid arthritis (RA...
Objectives: To investigate the ability of synovial fluid from patients with rheumatoid arthritis (RA...
Objectives: To investigate the ability of synovial fluid from patients with rheumatoid arthritis (RA...
<p>Monocytes and CD4<sup>+</sup> memory T cells were isolated from peripheral blood and synovial flu...
<p><b>A)</b> Single cell suspensions were prepared from synovial biopsies from RA patients (n = 4) a...
<p>Comparisons of the percentages and mean fluorescence intensity (MFI) of circulating MDL-1-express...
<p><b>A</b>) Representative forward and side scatter of synovial fluid cells (SFCs) with gating of l...
<p>Mononuclear cells were isolated from PB. Synovial tissue (ST) samples were obtained at arthroscop...
Objectives: This study, developed within the Innovative Medicines Initiative Joint Undertaking proje...
<p>A) Thawed A) Cryopreserved PBMC from control and RA patients were stimulated for 4hrs with LPS (1...