Pattern ERG recordings in normal and glaucomatous eyes.

<p>Changes observed in Pattern ERGs of untreated, AG or SNC-121-treated glaucomatous rat eyes are shown as a percentage of the contralateral control eye. In these experiments, Brown Norway rats were treated with AG (25 mg/kg, i.p.) or SNC-121 (1 mg/kg, i.p.), individually or together simultaneously, 30 minutes after hypertonic saline injections. Animals were treated with naltrindole 30 minutes after glaucomatous injury followed by SNC-121 treatment. The drug treatment was continued once daily for 7 days in all groups. Data are mean ± SE; *<i>P</i><0.05; n = 7–8.