<p>Illustration of haplotype forms identified by haploPS that span the longest genetic distances around <i>THADA</i> (brown horizontal bar) on chromosome 2. Uncharacteristically long haplotypes were found at the same frequency of 45% in two East Asian populations (CHD, CHS) to span <i>THADA</i>, whereas at the same frequency, the longest haplotypes present in European populations (CEU, TSI, MXL) were comparatively much shorter. The haplotypes for the two East Asian populations also carried the thymine allele at rs7578597 that has been reported in association studies to increase the risk to Type 2 diabetes.</p
South Asians are at high risk of developing type 2 diabetes (T2D). We carried out a genome-wide asso...
[[abstract]]Aims/hypothesis: Candidate gene and genome-wide association studies have identified ∼60 ...
South Asians are at high risk of developing type 2 diabetes (T2D). We carried out a genome-wide asso...
<p>Illustration of haplotype forms identified by haploPS that span the longest genetic distance arou...
Many disease-susceptible SNPs exhibit significant disparity in ancestral and derived allele frequenc...
Recent large genome-wide association studies (GWAS) have identified multiple loci which harbor genet...
Recent large genome-wide association studies (GWAS) have identified multiple loci which harbor genet...
<p>Risk-allele frequencies (RAF) were shown as heights of bars across the 11 HapMap populations at 1...
Many disease-susceptible SNPs exhibit significant disparity in ancestral and derived allele frequenc...
Recent large genome-wide association studies (GWAS) have identified multiple loci which harbor genet...
Type 2 diabetes (T2D) has become a major health problem throughout the world and the epidemic is par...
<div><p>Many disease-susceptible SNPs exhibit significant disparity in ancestral and derived allele ...
Candidate gene and genome-wide association studies have identified similar to 60 susceptibility loci...
Aims/hypothesisCandidate gene and genome-wide association studies have identified ∼60 susceptibility...
<p>Eleven independent cross-ethnic T2D risk alleles were combined as an ensemble to calculate the av...
South Asians are at high risk of developing type 2 diabetes (T2D). We carried out a genome-wide asso...
[[abstract]]Aims/hypothesis: Candidate gene and genome-wide association studies have identified ∼60 ...
South Asians are at high risk of developing type 2 diabetes (T2D). We carried out a genome-wide asso...
<p>Illustration of haplotype forms identified by haploPS that span the longest genetic distance arou...
Many disease-susceptible SNPs exhibit significant disparity in ancestral and derived allele frequenc...
Recent large genome-wide association studies (GWAS) have identified multiple loci which harbor genet...
Recent large genome-wide association studies (GWAS) have identified multiple loci which harbor genet...
<p>Risk-allele frequencies (RAF) were shown as heights of bars across the 11 HapMap populations at 1...
Many disease-susceptible SNPs exhibit significant disparity in ancestral and derived allele frequenc...
Recent large genome-wide association studies (GWAS) have identified multiple loci which harbor genet...
Type 2 diabetes (T2D) has become a major health problem throughout the world and the epidemic is par...
<div><p>Many disease-susceptible SNPs exhibit significant disparity in ancestral and derived allele ...
Candidate gene and genome-wide association studies have identified similar to 60 susceptibility loci...
Aims/hypothesisCandidate gene and genome-wide association studies have identified ∼60 susceptibility...
<p>Eleven independent cross-ethnic T2D risk alleles were combined as an ensemble to calculate the av...
South Asians are at high risk of developing type 2 diabetes (T2D). We carried out a genome-wide asso...
[[abstract]]Aims/hypothesis: Candidate gene and genome-wide association studies have identified ∼60 ...
South Asians are at high risk of developing type 2 diabetes (T2D). We carried out a genome-wide asso...