Crystal structure and the carbohydrate and E-cadherin binding sites of the HA/B complex.

<p>The galactose binding sites of HA1 (Asn286) are colored blue and marked with dotted blue circles. The sialic acid-binding sites of HA3 (Arg528) are colored magenta and marked with dotted magenta circles. The E-cadherin binding sites of HA3 (Leu473, M508, and Lys607) are colored red and marked with dotted red circles. These sites are structurally independent. Each of the three HA monomers is colored pale cyan, pale yellow, or pink.