<p><b>A</b>. Immonohistochemical localization of renin/prorenin in the aortas of normal, CKD and AST-120-treated CKD rats. <b>B</b>. Quantitative data of renin/prorenin-positive area in the aortas of normal (n = 9), CKD (n = 8) and AST-120-treated CKD rats (n = 8) (Mean±SE). ***p<0.001 vs normal, #p<0.05 vs CKD. <b>C</b>. Immonohistochemical localization of renin/prorenin in the aortas of DN, DN+IS, DH and DH+IS rats. <b>D</b>. Quantitative data of renin/prorenin-positive area in the aortas of DN, DN+IS, DH and DH+IS rats (mean±SE, n = 8). ***p<0.001vs DN, ##p<0.01 vs DH.</p
Abstract—Renin/prorenin binding to the (pro)renin receptor ([P]RR) results in direct (angiotensin-in...
<p><b>a</b> Immunohistochemical detection of proliferation and remodeling marker proteins including ...
Akihiro Tojo,1 Satoshi Kinugasa,1 Toshiro Fujita,2 Christopher S Wilcox3 1Division of Nephrology and...
Chronic kidney disease (CKD) is associated with an increased risk of cardiovascular disease (CVD). (...
Objective. The nephron (pro)renin receptor may play a pathophysiological role in renal disorders in ...
The renin-angiotensin system (RAS) is involved in the regulation of blood pressure and electrolyte b...
Recently, a (pro) renin receptor has been identified which mediates profibrotic effects independent ...
The discovery of a (pro)renin receptor [(P)RR] and the introduction of renin inhibitors in the clini...
SUMMARY Nephrectomized rats have above-normal plasma prorenin levels, presumably of extra-renal orig...
Long-term hypertension in arteries leads to remodelling of the arterial wall. We focused on morpholo...
The discovery of a (pro)renin receptor [(P)RR] and the introduction of renin inhibitors in the clini...
Recently, a (pro)renin receptor has been identified which mediates profibrotic effects independent o...
SUMMARY We have studied the contribution of circulating renin of renal origin to renin-like activity...
Background/Aims: We have reported that the long-term administration of angiotensin II receptor block...
Abstract—Renin/prorenin binding to the (pro)renin receptor ([P]RR) results in direct (angiotensin-in...
Abstract—Renin/prorenin binding to the (pro)renin receptor ([P]RR) results in direct (angiotensin-in...
<p><b>a</b> Immunohistochemical detection of proliferation and remodeling marker proteins including ...
Akihiro Tojo,1 Satoshi Kinugasa,1 Toshiro Fujita,2 Christopher S Wilcox3 1Division of Nephrology and...
Chronic kidney disease (CKD) is associated with an increased risk of cardiovascular disease (CVD). (...
Objective. The nephron (pro)renin receptor may play a pathophysiological role in renal disorders in ...
The renin-angiotensin system (RAS) is involved in the regulation of blood pressure and electrolyte b...
Recently, a (pro) renin receptor has been identified which mediates profibrotic effects independent ...
The discovery of a (pro)renin receptor [(P)RR] and the introduction of renin inhibitors in the clini...
SUMMARY Nephrectomized rats have above-normal plasma prorenin levels, presumably of extra-renal orig...
Long-term hypertension in arteries leads to remodelling of the arterial wall. We focused on morpholo...
The discovery of a (pro)renin receptor [(P)RR] and the introduction of renin inhibitors in the clini...
Recently, a (pro)renin receptor has been identified which mediates profibrotic effects independent o...
SUMMARY We have studied the contribution of circulating renin of renal origin to renin-like activity...
Background/Aims: We have reported that the long-term administration of angiotensin II receptor block...
Abstract—Renin/prorenin binding to the (pro)renin receptor ([P]RR) results in direct (angiotensin-in...
Abstract—Renin/prorenin binding to the (pro)renin receptor ([P]RR) results in direct (angiotensin-in...
<p><b>a</b> Immunohistochemical detection of proliferation and remodeling marker proteins including ...
Akihiro Tojo,1 Satoshi Kinugasa,1 Toshiro Fujita,2 Christopher S Wilcox3 1Division of Nephrology and...