Greater prenatal PAH exposure was associated with greater body weight in male and female F1 offspring.

<p>Weights of prenatal PAH and control mice were monitored from PND21 day until PND60. Body weight of PAH and control offspring differed significantly by two way ANOVA (GROUP*LITTER SIZE) on PND 25–27 and PND 52–60 for females and PND 30–60 for males. These included differences among females on PND25 (10.84±0.17 g, n = 19 following PAH vs. 8.87±0.90 g, n = 28 following control exposure), PND27 (10.84±0.17 g, n = 19 following PAH vs. 9.79±0.37 g, n = 28 following control exposure), PND52 (19.36±1.69 g, n = 32 following PAH vs. 17.29±1.79 g, n = 41 following control exposure), and PND 60 (22.79±1.92 g, n = 32 following PAH vs. 19.55±2.05 g, n = 41 following control exposure, p<0.05 for each). Examples of differences among males were found on PND30 (12.24±0.26 g, n = 28 following PAH vs. 11.64±0.35 g, n = 35 following control exposure) and PND60 (23.43±1.85 g, n = 28 in PAH vs 20.38±1.60 g, n = 35 following control exposure, p<0.05 for each). Means ± SD are plotted. *refers to p<0.05 determined at each time point.