<p>Vaccinated and mock-vaccinated mice in challenge groups were challenged thorough the intra-vaginal route with 10<sup>6</sup> PFU of HSV-1 McKrae (A) or HSV-2G (B) 21 days post primary vaccination and observed for 14 days. One hundred percent of the vaccinated animals in the HSV-1 and HSV-2 challenged group survived, while 100% of the mock-vaccinated animals died. (A) A statistically significant difference was observed between the vaccinated and mock-vaccinated groups (p<0.0001) using the Gehan-Breslow-Wilcoxin test. (B) A statistically significant difference was observed between the vaccinated and mock-vaccinated groups (p<0.0001) using the Gehan-Breslow-Wilcoxin test.</p
<p>A129 mice (n = 6) were challenged with double the minimum lethal dose of CCHFv 14 days after boos...
<p>C57BL/6 mice (○) or C57BL/6 mice depleted of CD4 and CD8 T cells (◊) were (A) vaccinated with 10<...
<p>Mice were treated with 2 mg medoxyprogesterone 7 and 3 days prior to vaginal HSV-2 challenge. On ...
<p>Groups of 10 BALB/c mice were vaccinated with 10<sup>6.5</sup> TCID<sub>50</sub> of NDV-H5 or NDV...
<p>Mice immunized as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.p...
<p>Groups of mice (n = 10) were infected by the intravaginal route with a single dose (ranging from ...
<p>(A) Pre challenge percent change in weight in mock vs vaccinated animals. Percentages normalized ...
<p>At 28 days after the last immunization (day 56), immunized mice were challenged intraperitoneally...
<p>Kunming mice (17 groups of eight mice, 10–12 g) were infected with ...
<p>Kaplan-Meier survival curves for adult mice immunized with 1 or 2 doses of PBS (black squares) or...
<p>Ten mice/group were inoculated intravaginally with 10<sup>3</sup> pfu/mouse of HSV1-LacZ, HSV1-Ta...
<p>Mice were either orally vaccinated with 10<sup>10</sup> BRD509 (⬜) or IV vaccinated with 10<sup>2...
<p>Kaplan-Meier survival curves for adult-primed or infant-primed mice immunized with 3 doses of eit...
<p>Mice (n = 5) were vaccinated i.d. (A) or i.n. (B) with 10-fold serial dilutions of Schu S4 Δ<i>pu...
<p>Kaplan-Meier survival curves for adult-primed (A) or infant-primed (B) mice immunized with 1, 2, ...
<p>A129 mice (n = 6) were challenged with double the minimum lethal dose of CCHFv 14 days after boos...
<p>C57BL/6 mice (○) or C57BL/6 mice depleted of CD4 and CD8 T cells (◊) were (A) vaccinated with 10<...
<p>Mice were treated with 2 mg medoxyprogesterone 7 and 3 days prior to vaginal HSV-2 challenge. On ...
<p>Groups of 10 BALB/c mice were vaccinated with 10<sup>6.5</sup> TCID<sub>50</sub> of NDV-H5 or NDV...
<p>Mice immunized as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.p...
<p>Groups of mice (n = 10) were infected by the intravaginal route with a single dose (ranging from ...
<p>(A) Pre challenge percent change in weight in mock vs vaccinated animals. Percentages normalized ...
<p>At 28 days after the last immunization (day 56), immunized mice were challenged intraperitoneally...
<p>Kunming mice (17 groups of eight mice, 10–12 g) were infected with ...
<p>Kaplan-Meier survival curves for adult mice immunized with 1 or 2 doses of PBS (black squares) or...
<p>Ten mice/group were inoculated intravaginally with 10<sup>3</sup> pfu/mouse of HSV1-LacZ, HSV1-Ta...
<p>Mice were either orally vaccinated with 10<sup>10</sup> BRD509 (⬜) or IV vaccinated with 10<sup>2...
<p>Kaplan-Meier survival curves for adult-primed or infant-primed mice immunized with 3 doses of eit...
<p>Mice (n = 5) were vaccinated i.d. (A) or i.n. (B) with 10-fold serial dilutions of Schu S4 Δ<i>pu...
<p>Kaplan-Meier survival curves for adult-primed (A) or infant-primed (B) mice immunized with 1, 2, ...
<p>A129 mice (n = 6) were challenged with double the minimum lethal dose of CCHFv 14 days after boos...
<p>C57BL/6 mice (○) or C57BL/6 mice depleted of CD4 and CD8 T cells (◊) were (A) vaccinated with 10<...
<p>Mice were treated with 2 mg medoxyprogesterone 7 and 3 days prior to vaginal HSV-2 challenge. On ...