Morphometric analysis of the spinal cord lesion.

<p>(<b>A</b>) LFB/HE staining of cross sections of the injured spinal cord at various distances to the injury epicentre (both rostrally and caudally) is depicted for all experimental groups at seven weeks post-injury. The area of spared spinal cord tissue was traced and measured. (<b>B</b>) The percentage of spared tissue was calculated by normalizing the area of spared tissue to the total cross sectional area of the spinal cord. Although our quantitative analysis showed a positive trend in increasing tissue preservation in groups that received ChABC+GFs/Trained and ChABC+GFs/Untrained compared to Vehicle/Untrained counterpart in 1 mm rostral area, the difference was not statistically significant (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0111072#pone-0111072-g001" target="_blank">Fig. 1B</a>, Two-Way ANOVA, N = 3–6/group).