Morbidity based on weight change following post exposure (p.e.) treatments of BALB/c mice.

<p>Mice were infected with 4–20 i.n. ECTV LD₅₀. (A, B) CPGs treatments with or without VACV-Lister on day 2 (A) and 3 (B) p.e. (C) Poly(I:C) treatments with or without VACV-Lister or VACV-Lister alone on day 2 p.e. (D) Poly(I:C) treatments with or without VACV-Lister or MVA and only vaccines treatments on day 3 p.e. (E, F) Poly(I:C) treatments with or without VACV-Lister or MVA and only MVA on day 4 (E) and 5 (F) p.e. Asterisk denote for significant difference in the area-under-the curve of weight changes along the entire experiment of the treated groups vs. the infected untreated group (* P<0.05, ** P<0.01, *** P<0.001, **** P<0.0001, <i>t</i>-test). Data collection for each treatment (weight change (mean, SE)) is indicated. Morbidity of Infected untreated mice from corresponding relevant experiments is shown. The number of mice succumbed to the infection in each time point is outlined color coded in a box above each graph. Survivals out of the total mice in each group are designated color coded next to the legend.