Systemic IFN-gamma does not sufficiently protect lupus-prone mice.

<p>IFN-gamma levels were measured in the serum of lupus-prone mice 7 days post infection (dpi) by multiplex. No significant differences were found between infected B6.<i>lpr</i> mice and infected WT controls (A). BXSB mice had reduced levels of systemic IFN-gamma (B). B6.<i>lpr</i> mice were 20 weeks of age and BXSB mice were 14 weeks of age. Each experiment was carried out at least 3 times with 3–6 mice per group.