Core gene phylogeny of the 95 sequenced non-O157 STEC and 14 <i>E. coli</i> reference genomes.

<p>The tree was rooted in Figtree (<a href="http://tree.bio.ed.ac.uk/software/figtree/" target="_blank">http://tree.bio.ed.ac.uk/software/figtree/</a>) by midpoint rooting. For an unrooted version of the phylogenetic tree, see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0111788#pone.0111788.s001" target="_blank">Figure S1</a>. The <i>E. coli</i> phylogroups are marked with the colours blue (A), green (B1), orange (B2), yellow (D), ochre (F) and indigo (E). Bootstrap values were scaled from 0–1, and blue circles indicate a bootstrap value of ≥0.8. LEE positive STEC were marked with •, while all HUS and HUS-associated STEC included in the study were indicated with red letters.