Morphological changes of middle ear mucosa in rats.

<p>Hematoxylin and eosin, original magnification, A, B, C: ×100 and D, E, F: ×400 (A, D). Normal morphological structure is displayed in control group. (B, E) In TS group, inflammatory cell infiltration, fibroblast proliferation and vascularization can be seen, as well as significantly increased membrane thickness. (C, F) The two panels show that, in captopril and losartan treated group, not only inflammatory cells, neovascularization and collagen fibers are decreased, but also the stroma is much thinner than that of the TS group. Double-headed arrow: membrane thickness; arrow: vascularization.