Results from SAXS experiments.

<p><b>Row A)</b> Collagen fibril stress) vs. D-period. Normalized collagen fibril stress was calculated using the rule of mixtures. The numerical gradient (slope) of the D-period vs. collagen fibril stress curves was used to measure fibril stiffness. Peak stiffness was used as the parameter for statistical interference testing. The second experimental set (w/o a 24 h MGO group) is not plotted here since over all the stresses were approximately one third lower but with equal group effects (two-way ANOVA: interactions term, p = 0.531). <b>B1)</b> Ratio of the integrated intensities for the 2^nd and 3^rd order meridional collagen reflections. <b>B2)</b> Relative contribution of overlap (O) region to the D-period (O/D) vs. D-period, when assuming a two-phasic approximation of the D-period electron density <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0110948#pone.0110948-Sasaki1" target="_blank">[17]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0110948#pone.0110948-Sherwood1" target="_blank">[63]</a>. <b>B3)</b> Peak widths (FWHM) from fitted Gaussians measured during the tensile experiments vs. D-period length. <b>Note:</b> The grayed area in the insets represents the range of yield point of the control samples as reference.