Expression of miR-21 regulated by STAT3 during transformation.

<p><b>(A)</b> Levels of miR-21 expression in CNE1 cells after treatment with siSTAT3 and siNC. siSTAT3 indicates that STAT3 is inhibited by siRNA, while siNC indicates that STAT3 is not inhibited by siRNA. Data are means ± SD. Asterisks indicate values that are significantly different from the values of siNC group. <b>(B)</b> Levels of miR-21 expression without (-IL-6) and with (+IL-6) IL-6 treatment of CNE1 cells. -IL-6 indicates that STAT3 is not activated by IL-6, while +IL-6 indicates that STAT3 is activated by IL-6. Data are means ± SD. Asterisks indicate values that are significantly different from the group without IL-6 treatment.