Natural variants in the G and H helices and C terminal extremity altering the sequence length of α-Hb.

<p>The data were collected from HbVar, the globin gene server <a href="http://globin.cse.psu.edu/globin/hbvar/" target="_blank">(http://globin.cse.psu.edu/globin/hbvar/</a>).</p><p>These different mutations led to an α-thalassemic phenotype more or less pronounced.</p><p>*the production of α-globin is under the control of two genes α1 and α2-globin genes (<i>HBA1</i> and <i>HBA2</i> respectively)</p><p>**Length expressed as number of amino-acid residues;</p><p>del, deletion; ins, insertion;</p><p>Natural variants in the G and H helices and C terminal extremity altering the sequence length of α-Hb.