Histological images of femur sections stained with Safranin-O.

<p>(A) Femur sections from control group at 0, 4 and 8 weeks after the primary injection. (B) Femur sections from CIA group at 0, 4 and 8 weeks after the primary injection. (C) Average thickness of femoral cartilage assessed by histology. Data are presented as the the mean±SD. 2D CT image before image preprocessing. 2D CT image before image preprocessing. #: P<0.05 for differences between the control group and the CIA group. Scale bar: 20 µm.