Heat map representing the log₂ fold-change values between contrasted treatments for the 844 genes found to be differentially expressed in at least one of the contrasts.

<p>Each of the 16 columns represents a different contrast between treatment groups, as indicated in the key to the right, and as illustrated in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0109978#pone-0109978-g001" target="_blank">Figure 1</a>; note that the 13A7 group was the denominator in most of these contrasts. The value of fold-change between contrasted treatments for each gene was indicated by the coloured scale, with red indicating a value>1 and blue indicating a value <1. Genes were clustered into 1-6 groups using the K-means technique, each possessing broadly the same profile across all contrasts.