Significant co-occurrence and co-exclusion relationships between bacterial OTUs and metabolites.

<p>Spearman’s rank correlation matrix of significant relationships between OTUs (at genus level) and metabolites. Strong correlations are indicated by large circles, whereas weak correlations are indicated by small circles. The colors of the scale bar denote the nature of the correlation, with 1 indicating a perfectly positive correlation (dark blue) and −1 indicating a perfectly negative correlation (dark red) between microbial genera and metabolites. Only significant correlations (FDR<0.05) are shown.