<p>Mice with CIA were treated with leflunomide (LEF), nimesulide (NIM), or leflunomide+nimesulide (LEF+NIM) and compared to untreated arthritic and normal mice. Hyperalgesia (A) and joint stiffness (B) were recorded at pre-arthritic, mid-arthritic and late arthritic phases of arthritis and compared to base line readings. Data are presented as mean ± SD. * Significantly different from normal mice; ** significantly different from CIA-mice.</p
<p>(<b>A</b>) Arthritis score in mice after arthritis induction with either mannan (open circles) or...
<p>Allo-tDCs were stimulated by LPS and pulsed with either CII peptide, OVA (as an irrelevant antige...
<p>AIA mice were treated as described in Material and Methods. The numbers of neutrophils in the syn...
<p>Mice with CIA were treated with leflunomide (LEF: Panel C), nimesulide (NIM: Panel D), or lefluno...
<p>Mice with CIA were treated with leflunomide (LEF), nimesulide (NIM), or leflunomide+nimesulide (L...
Mean clinical severity score of mice induced with CIA demonstrating a consistent level of moderate a...
<p>Incidence (A) of CIA and severity in affected mice (B). No significant differences could be found...
<p>The incidence of arthritis (A), the hind paw clinical score (B) and the hind paw thickness (C) in...
<p>DBA1 mice with established CIA were injected i.p. either with PBS (control) or with AIQ (1.5 mg/k...
<p>The data are presented as arthritis score of s.c. treated CIA mice, measured from day (0) (diseas...
<p>A) Inhibition of arthritis in the CIA model. Mean clinical score of each group (n = 12), shown as...
<p>A) Scheme representing the experimental protocol followed, which is described in material and met...
Nimesulide is a COX-2 inhibitor used for symptomatic relief of rheumatoid arthritis. Leflunomide is ...
International audienceBackground: In the collagen-induced arthritis (CIA) mouse model, inflammation ...
<p>A) Evaluation of the increase of the paw swelling of CIA control mice or mice injected with synge...
<p>(<b>A</b>) Arthritis score in mice after arthritis induction with either mannan (open circles) or...
<p>Allo-tDCs were stimulated by LPS and pulsed with either CII peptide, OVA (as an irrelevant antige...
<p>AIA mice were treated as described in Material and Methods. The numbers of neutrophils in the syn...
<p>Mice with CIA were treated with leflunomide (LEF: Panel C), nimesulide (NIM: Panel D), or lefluno...
<p>Mice with CIA were treated with leflunomide (LEF), nimesulide (NIM), or leflunomide+nimesulide (L...
Mean clinical severity score of mice induced with CIA demonstrating a consistent level of moderate a...
<p>Incidence (A) of CIA and severity in affected mice (B). No significant differences could be found...
<p>The incidence of arthritis (A), the hind paw clinical score (B) and the hind paw thickness (C) in...
<p>DBA1 mice with established CIA were injected i.p. either with PBS (control) or with AIQ (1.5 mg/k...
<p>The data are presented as arthritis score of s.c. treated CIA mice, measured from day (0) (diseas...
<p>A) Inhibition of arthritis in the CIA model. Mean clinical score of each group (n = 12), shown as...
<p>A) Scheme representing the experimental protocol followed, which is described in material and met...
Nimesulide is a COX-2 inhibitor used for symptomatic relief of rheumatoid arthritis. Leflunomide is ...
International audienceBackground: In the collagen-induced arthritis (CIA) mouse model, inflammation ...
<p>A) Evaluation of the increase of the paw swelling of CIA control mice or mice injected with synge...
<p>(<b>A</b>) Arthritis score in mice after arthritis induction with either mannan (open circles) or...
<p>Allo-tDCs were stimulated by LPS and pulsed with either CII peptide, OVA (as an irrelevant antige...
<p>AIA mice were treated as described in Material and Methods. The numbers of neutrophils in the syn...