GSEA analysis of the genes differentially expressed in the absence of Med7 in <i>C. albicans</i>.

<p>Example GSEA enrichment plots for selected genes sets differentially expressed in the <i>med7</i> GRACE mutant grown in yeast cell conditions is presented. On the x-axis are genes ranked according to their expression in the <i>med7</i> GRACE mutant, from the up-regulated genes on the left hand side to the down-regulated genes on far right. Black vertical lines show the positions of the individual genes in the gene set. The cumulative value of the enrichment score (y-axis) is represented by the green line. A positive normalized enrichment score (NES) indicates enrichment in the up-regulated group of genes in the <i>med7</i> GRACE mutant (A), while a negative NES indicates prevalence of the genes in the down-regulated group (B). The title for each of the graphs indicates the genes set used to compare to the <i>med7</i> GRACE mutant set. FDR is the false discovery rate. The full Correlation is presented in the <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1004770#pgen.1004770.s010" target="_blank">Table S5</a>.