Amelioration of LT-induced erythrocytopenic response by G-CSF.

<p>The experimental outlines are indicated (A), (E). Mice were treated with saline (n = 12), G-CSF (n = 11), LT (n = 11), and G-CSF plus LT (n = 12) before (A) or saline (n = 8), G-CSF (n = 8), LT (n = 8), and LT plus G-CSF (n = 8) after (E) the LT challenges; their WBC, RBC, and platelet counts were subsequently analyzed at 22, 44, and 66 h after the LT challenges. Saline-treated mice were used as negative controls. *<i>P</i><0.05, **<i>P</i><0.01 were compared between the indicated groups. Data are shown as mean ± SD and represent the results from 2 independent experiments.