<i>In vivo</i> collagen synthesis and cell proliferation by immunohistochemistry.

<p>Representative samples were taken from 3 week injured flexor tendons. A. Sham treated flexor tendon injury stained with antibodies to Hsp47 (collagen synthesis marker). Arrow indicates adhesion. B Adaprev treated flexor tendon injury. C Quantitative analysis of Hsp47 in tendon and subcutaneous tissues showing no significant difference in cellular Hsp47 expression between the two groups. D. Sham treated flexor tendon injury stained with antibodies to BrdU (cellular proliferation marker). Arrow indicates adhesion. Note good staining of basal layer of skin, hair follicles and on the tendon surface. E. Adaprev treated flexor tendon injury. F. Quantitative analysis of if BrdU in tendon and subcutaneous tissues showing no significant difference in cellular BrdU expression between the two groups (p>0.05). Error bars represent standard error of mean. Scale bar represents 200 µm.