SS treatment ameliorates learning and memory impairment in Morris Water Maze and Object recognition test.

<p>(<b>A</b>) MWM test for SS and vehicle-treated APP/PS1 and WT mice. The mean escape latency was given for different test days. (<b>B</b>) The mean percent time in probe trial of MWM on day 7. TQ: Target quadrant; AL: Adjacent left; AR: Adjacent right; OP: Opposite. (<b>C</b>) Representative mice search paths from different groups. (<b>D and E</b>) The latency to target quadrant (<b>D</b>) and the frequency to pass the target position (<b>E</b>) in probe trial are shown. (<b>F and G</b>) The swimming velocity (<b>F</b>) and distance (<b>G</b>) in probe trial are shown. (<b>H and I</b>) Novel object recognition analysis. Preference scores of training phase (<b>H</b>) and Recognition Index of testing phase (<b>I</b>) during a 10-min testing phase are shown, respectively. n = 9–12 for each group. *<i>P</i><0.05, **<i>P</i><0.01, ***<i>P</i><0.001, #<i>P</i><0.05, ##<i>P</i><0.01, ###<i>P</i><0.001.