Effect of polymyxin B on simplexide- and LPS-induced release of IL-6, CXCL8 and TNF-α from monocytes.

<p>Monocytes were incubated for 8 h (TNF-α) or 24 h (IL-6 and CXCL8) with simplexide (10 µM) or LPS (100 ng/ml) either in the absence (Control) or the presence of polymyxin B (50 µg/ml). Data are the mean ± SE of three experiments.</p><p>* p<0.05 vs. respective untreated.</p>†<p>p<0.05 vs. respective control.</p><p>Effect of polymyxin B on simplexide- and LPS-induced release of IL-6, CXCL8 and TNF-α from monocytes.