Figure 1a. Longitudinal change between baseline and 24 months in cartilage volume grouped by mitochondrial DNA (mtDNA) haplogroups.

<p>MFTC.VCtAB: normalized cartilage volume in medial tibia femoral compartment; cMF.VCtAB: normalized cartilage volume in central medial femoral; MFTC.VC: cartilage volume in medial tibia femoral compartment; cMF.VC: volume of cartilage in central medial femoral. MFTC.VC and cMF.VC that are shown in cubic millimeters (mm3) and MFTC.VCtAB and cMF.VCtAB are shown in square centimeters (cm2); (*) indicates statistical significance (p<0.05). Values are mean change+SE (standard error). <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0112735#pone-0112735-g001" target="_blank"><b>Figure 1b</b></a>. Longitudinal change between baseline and 24 months in cartilage thickness grouped by mitochondrial DNA (mtDNA) haplogroups. cMFTC.ThCtAB: mean cartilage thickness in central medial tibia femoral compartment (weight-bearing); MFTC.ThCtAB: mean cartilage thickness in medial tibia femoral compartment; aMT.ThCtAB: mean cartilage thickness in medial tibia (anterior); ccMF.ThCtAB: mean cartilage thickness in central medial femoral (center). All of them represented in millimeters (mm); (*) indicates statistical significance (p<0.05). Values are mean change+SE (standard error).